Free Access
Volume 82, Number 2, March-April 2002
Page(s) 151 - 170


Barbosa M., "Cardo'' (Cynara cardunculus L.) as vegetable rennet, Boletim do Departamento de Tecnologia e Indústria Alimentar, LNETI-DTIA, Lisboa, Portugal, 1983.
Barbosa M., Valles E., Vassal L., Mocquot G., L'utilisation d'extrait de Cynara cardunculus L. comme agent coagulant en fabrication de fromages à pâte molle et à pâte cuite, Lait 56 (1976) 1-17.
Barbosa M., Corradini C., Battistoni B., Cheesemaking experiments carried out on some Italian cheeses with vegetable rennet from cardo (Cynara cardunculus L.), Sci. Tec. Latt.-Casearia 32 (1981) 203-221.
Boisnard M., Petrissant G., Complete sequence of ovine-casein messenger RNA, Biochimie 67 (1985) 1043-1051.
Bouniol C., Sequence of the goat $\alpha_{{\rm s2}}$-casein-encoding cDNA, Gene 125 (1993) 235-242.
Campos R., Guerra R., Aguiar M., Ventura O., Camacho L., Chemical characterization of proteases extracted from wild thistle (Cynara cardunculus), Food Chem. 35 (1990) 89-97.
Carmona M.A., Sanjuan E., Gomez R., Fernandez-Salguero J., Effect of starter cultures on the physico-chemical and biochemical features in ewe cheese made with extracts from flowers of Cynara cardunculus L., J. Sci. Food Agric. 79 (1999) 737-744.
Carrera E., Gaya P., Medina M., Núñez M., Effect of milk coagulant on the formation of hydrophobic and hydrophilic peptides during the manufacture of cow's milk Hispanico cheese, Milchwissenchaft 54 (1999) 146-149.
Castanheira P.M.D., Distribuiç ao diferencial das cardosinas A e B ao longo do pistilo de Cynara cardunculus L., MSc thesis, Universidade de Coimbra, Coimbra, Portugal, 1998.
Christen C., Virasoro E., Présure végétale. Extraction et proprietés (I), Lait 15 (1935) 354-363.
Christen C., Virasoro E., Présure végétale. Extraction et proprietés (II), Lait 15 (1935) 496-505.
Cordeiro M.C., Pais M.S., Brodelius P.E., Cinarases (proteases) de Cynara cardunculus L.: estudo da actividade enzimática em vários ecotipos de Portugal. First International Symposium NOPROT, Faro, Portugal, September 2-6, 1991.
Cordeiro M.C., Jakob E., Puhan Z., Pais M.S., Brodelius P.E., Milk clotting and proteolytic activities of purified cynarases from Cynara cardunculus - a comparison to chymosin, Milchwissenschaft 47 (1992) 683-700.
Dalgleish D.G., The enzymatic coagulation of milk, in: Fox P.F. (Ed.), Cheese Chemistry, Physics and Microbiology, Vol. 1, 2nd ed., Elsevier, London, 1993, pp. 69-100.
Delacroix-Buchet A., Trossat P., Proteolysis and texture of Gruyere type cheeses. 1. Influence of water activity, Lait 71 (1991) 299-311.
Desmazeaud M.J., Gripon J.C., General mechanism of protein breakdown during cheese ripening, Milchwissenschaft 32 (1977) 731-734.
Esteves C., Estudo comparativo das características bioquímicas dos coalhos de Cynara cardunculus L., Cynara scolymus L., e Cynara humilis L. MSc thesis, Universidade de Coimbra, Portugal, 1995.
Exterkate F.A., Alting A.C., The role of starter peptidases in the initial proteolytic events leading to amino acids in Gouda cheese, Int. Dairy J. 5 (1995) 15-28.
Faro C.J., Purificaç ao e caracterizaç ao físico-química da protease de Cynara cardunculus L. Ph.D. thesis, Universidade de Coimbra, Portugal, 1991.
Faro C.J., Moir A.J.G., Pires E.V., Specificity of a milk clotting enzyme extracted from the thistle Cynara cardunculus L.: Action on oxidised insulin and $\kappa$-casein, Biotechnol. Lett. 14 (1992) 841-846.
Faro C.J., Veríssimo P., Lin Y., Tang J., Pires E.V., in: Takahashi K. (Ed.), Aspartic proteinases: Structure, Function, Biology and Biomedical Implications, Plenum Press, New York, USA, 1995, pp. 373-377.
Fenelon M.A., Guinee T.P., Primary proteolysis and textural changes during ripening in Cheddar cheese manufactured to different fat contents, Int. Dairy J. 10 (2000) 151-158.
Fernandez del Pozo B., Gaya P., Medina M., Rodríguez-Marin M.A., Nú nez M., Changes in chemical and rheological characteristics of La Serena ewe's milk cheese during ripening, J. Dairy Res. 55 (1988) 457-464.
Fernández-Salguero J., Sanjuán E., Influence of vegetable and animal rennet on proteolysis during ripening in ewe's milk cheese, Food Chem. 64 (1999) 177-183.
Fernández-Salguero J., Sanjuán E., Montero E., A preliminary study of the chemical composition of Guía cheese, J. Food Compos. Anal. 4 (1991) 262-269.
Gaya P., Carrera E., Medina M., Nu nez M., Formation of hydrophobic peptides during the manufacture of ewe's milk Manchego cheese using different milk coagulants, Milchwissenchaft 54 (1999) 556-558.
Heimgartner U., Pietrzak M., Geertsen R., Brodelius P., Silva Figueiredo A.C., Pais M.S.S., Purification and partial characterization of milk clotting proteases from flowers of Cynara cardunculus, Phytochemistry 29 (1990) 1405- 1410.
Kelly A.L., The influence of heat treatment of milk on proteolysis in Cheddar cheese during ripening, Milchwissenchaft 54 (1999) 682-685.
Lawrence R.C., Creamer L.K., Gilles J., Texture development during ripening, J. Dairy Sci. 70 (1987) 1748-1760.
Macedo A., Malcata F.X., Oliveira J.C., The technology, chemistry, and microbiology of Serra cheese: a review, J. Dairy Sci. 76 (1993) 1725-1739.
Macedo I.Q., Faro C.J., Pires E.V., Specificity and kinetics of the milk-clotting enzyme from Cardoon (Cynara cardunculus L.) toward bovine $\kappa$-casein, J. Agric. Food Chem. 41 (1993) 1537-1540.
Macedo I.Q., Faro C.J., Pires E.V., Caseinolytic specificity of cardosin, an aspartic protease from the cardoon Cynara cardunculus L.: action on bovine $\alpha_{{\rm s}}$- and $\beta$-casein and comparison with chymosin, J. Agric. Food Chem. 44 (1996) 42-47.
Martins A.P.L., Vasconcelos M.M.P., Sousa R.B., Thistle (Cynara cardunculus L.) flower as a coagulant agent for cheesemaking: Short characterization, Lait 76 (1996) 473-477.
Mercier J.C., Gaye P., Soulier S., Hue-Delahaie D., Vilotte J.L., Construction and identification of recombinant plasmids carrying cDNAs coding for ovine $\alpha_{{\rm s}}$-, $\beta$-, $\kappa$-casein and $\beta$-lactoglobulin. Nucleotide sequence of $\alpha_{{\rm s}}$-casein cDNA, Biochimie 67 (1985) 959-971.
Noomen A., Activity of proteolytic enzymes in simulated soft cheeses (Meshanger type). 2. Activity of calf rennet, Neth. Milk Dairy J. 32 (1978) 26-48.
Nú nez M., Fernández-del-Pozo B., Rodríguez-Marin M.A., Gaya, P., Medina M., Effect of vegetable and animal rennet on chemical, microbiological, rheological and sensory characteristics of La Serena cheese, J. Dairy Res. 58 (1991) 511-519.
O'Keeffe R.B., Fox P.F., Daly C., Contribution of rennet and starter proteases to proteolysis in Cheddar cheese, J. Dairy Res. 43 (1976) 97-107.
Ramalho-Santos M., Veríssimo P., Faro C., Pires E., Action on bovine $\alpha_{{\rm s1}}$-casein of cardosins A and B, aspartic proteinases from the flowers of the cardoon Cynara cardunculus L, Biochim. Biophys. Acta 1297 (1996) 83-89.
Ramalho-Santos M., Veríssimo P., Faro C., Pires E., Action on bovine $\beta$-casein of cardosins A and B, X Congresso Nacional de Bioquímica, Braga, Portugal, 31st October-2nd November, 1996.
Ramalho-Santos M., Pissarra J., Verissimo P., Pereira S., Salema R., Pires E., Faro C.J., Cardosin A, an abundant aspartic proteinase, accumulates in protein storage vacuoles in the stigmatic papillae of Cynara cardunculus L., Planta 203 (1997) 204-212.
Richardson B.C., Mercier J.C., The primary structure of the ovine $\beta$-caseins, Eur. J. Biochem. 99 (1979) 285-297.
Roa I., López M.B., Mendiola F.J., Residual clotting activity and ripening properties of vegetable rennet from Cynara cardunculus in La Serena cheese, Food Res. Int. 32 (1999) 413-419.
Rolland M.P., Bitri L., Besançon P., Monospecificity of the antibodies to bovine $\alpha_{{\rm s1}}$-casein fragment 140-149: application to the detection of bovine milk in caprine dairy products, J. Dairy Res. 62 (1995) 83-91.
Roseiro M.L.B., Ewe's milk cheesemaking in Portugal using a vegetable rennet (a review), Sheep Dairy News 8 (1991) 65-80.
Silva S.V., Malcata F.X., On the use of reversed-phase HPLC to characterize the specificity of cardosins from Cynara cardunculus toward ovine caseins, XXVII Scientific Meeting of Chromatography, Lugo, Spain, 1998.
Silva S.V., Malcata F.X., On the activity and specificity of cardosin B, a plant proteinase, on ovine caseins, Food Chem. 67 (1999) 373-378.
Silva S.V., Malcata F.X., Comparative catalytic action of two plant proteinases upon caprine caseins in solution, Food Chem. 71 (2000) 207-214.
Sousa M.J.C.F., Plant rennet substitute from flowers of Cynara cardunculus. MSc thesis, National University of Ireland, Cork, Ireland, 1993.
Sousa M.J.C.F., Characterization of the proteolytic action of the flowers of Cynara cardunculus in ovine, caprine and bovine cheeses. Ph.D. thesis, Escola Superior de Biotecnologia, Porto, Portugal, 1998.
Sousa M.J., Malcata F.X., Effects of processing conditions on the caseinolytic activity of proteinases from Cynara cardunculus L., Food Sci. Technol. Int. 2 (1996) 255-263.
Sousa M.J., Malcata F.X., Influence of pasteurization of milk and addition of starter cultures on protein breakdown in ovine cheeses manufactured with extracts from flowers of Cynara cardunculus, Food Chem. 57 (1996) 549-556.
Sousa M.J., Malcata F.X., Comparative biochemical evolution during ripening of bovine, ovine and caprine cheeses manufactured with extracts of flowers of Cynara cardunculus, Z. Lebensm. Unters. Forsch. 205 (1997) 97-103.
Sousa M.J., Malcata, F.X., Comparison of plant and animal rennets in terms of microbiological, chemical and proteolysis characteristics of ovine cheese, J. Agric. Food Chem. 45 (1997) 74-81.
Sousa M.J., Malcata F.X., Ripening of ovine milk cheeses: Effects of plant rennet, pasteurization and addition of starter on lipolysis, Food Chem. 58 (1997) 427-432.
Sousa M.J., Malcata F.X., Proteolysis of ovine and caprine caseins in solution by enzymatic extracts of Cynara cardunculus, Enzyme Microb. Technol. 22 (1998) 305-314.
Sousa M.J., Malcata F.X., Identification of peptides from ovine milk cheese manufactured with animal rennet or extracts of Cynara cardunculus as coagulant, J. Agric. Food Chem. 46 (1998) 4034-4041.
Sousa M.J., Balc ao V.M., Malcata F.X., Evolution of free fatty acid profile during ripening in cheeses manufactured from bovine, ovine and caprine milks with extracts of Cynara cardunculus, Z. Lebensm. Unters. Forsch. 205 (1997) 104-107.
Swaisgood H.E., Chemistry of the caseins, in: Fox P. F. (Ed.), Advances in Dairy Chemistry, Chapman and Hall, London, UK, vol. 1, 1993, pp. 63-110.
Tavaria F., Sousa M.J., Domingos A., Malcata F.X., Brodelius P., Clemente A., Pais M.S., Degradation of caseins from milk of different species by extracts of Centaurea calcitrapa, J. Agric. Food Chem. 45 (1997) 3760-3765.
Tavaria F.K., Sousa M.J., Malcata F.X., Storage and lyophilization effects of extracts of Cynara cardunculus on the degradation of ovine and caprine caseins, Food Chem. 72 (2001) 79-88.
Trujillo A.J., Guamis B., Carretero C.J., Proteolysis of goat $\beta$-casein by calf rennet under various factors affecting the cheese ripening process, J. Agric. Food Chem. 43 (1995) 1472-1478.
Tsouli J., Étude comparée de l'activité enzymatique de trois varietés d'artichauts du genre Cynara cardunculus L. sur la coagulation du lait, Lait 44 (1974) 415-421.
Veríssimo P., Esteves C., Faro C., Pires E., The vegetable rennet of Cynara cardunculus L. contains two proteinases with chymosin and pepsin-like specificities, Biotechnol. Lett. 17 (1995) 621-626.
Veríssimo P., Faro C., Moir A.J., Lin Y., Tang J., Pires E., Purification, characterization and partial amino acid sequencing of two new aspartic proteinases from fresh flowers of Cynara cardunculus L., Eur. J. Biochem. 235 (1996) 762-768.
Vieira-de-Sá F., Barbosa M., Cheese-making experiments with a vegetable rennet from cardo (Cynara cardunculus L.), J. Dairy Res. 39 (1972) 335-343.
Vioque M., Gómez R., Sánchez E., Mata C., Tejada L., Fernández-Salguero J., Chemical and microbiological characteristics of ewe's milk cheese manufactured with extracts from flowers of Cynara cardunculus and Cynara humilis, J. Agric. Food Chem. 48 (2000) 451-456.
Visser F.M.W., Contribution of enzymes from rennet, starter bacteria and milk to proteolysis and flavour development in Gouda cheese. 3. Protein breakdown: analysis of the soluble nitrogen and amino acid nitrogen fraction, Neth. Milk Dairy J. 31 (1977) 210-239.
Visser S., Proteolytic enzymes and their action on milk proteins (a review), Neth. Milk Dairy J. 35 (1981) 65-88.
Visser S., Hup G., Exterkate F.A., Bitter flavour in cheese. 2. Model studies on the formation and degradation of bitter peptides by proteolytic enzymes from calf rennet, starter cells and starter cell fractions, Neth. Milk Dairy J. 37 (1983) 169-180.
Visser S., Slangen K., Hup G., Stadhouders J., Bitter flavour in cheese. 3. Comparative gel-chromatographic analysis of hydrophobic peptide fractions from twelve Gouda-type cheeses and identification of bitter peptides isolated from a cheese made with a Streptococcus cremoris strain HP, Neth. Milk Dairy J. 37 (1983) 181-192.


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