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Cited article:

Bracken Fern Carcinogen, Ptaquiloside, Forms a Guanine O6-Adduct in DNA

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Journal of Agricultural and Food Chemistry 73 (2) 1053 (2025)
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Geographical distribution of caudatoside and ptaquiloside in bracken ferns in Northern Europe

Vaidotas Kisielius, Bo Markussen, Hans Christian Bruun Hansen and Lars Holm Rasmussen
Environmental Sciences Europe 36 (1) (2024)
https://doi.org/10.1186/s12302-024-01012-6

Sixty years of research on bracken fern (Pteridium spp.) toxins: Environmental exposure, health risks and recommendations for bracken fern control

Rui M. Gil da Costa, Andrew Povey, Beatriz Medeiros-Fonseca, Carmel Ramwell, Connie O'Driscoll, David Williams, Hans Chr B. Hansen, Lars Holm Rasmussen, Mary T. Fletcher, Peter O'Connor, Richard H.W. Bradshaw, Roderick Robinson and James Mason
Environmental Research 257 119274 (2024)
https://doi.org/10.1016/j.envres.2024.119274

Health and Environmental Hazards of the Toxic Pteridium aquilinum (L.) Kuhn (Bracken Fern)

Matěj Malík, Otakar Jiří Mika, Zdeňka Navrátilová, Uday Kumar Killi, Pavel Tlustoš and Jiří Patočka
Plants 13 (1) 18 (2023)
https://doi.org/10.3390/plants13010018

Occurrence and stability of ptesculentoside, caudatoside and ptaquiloside in surface waters

Vaidotas Kisielius, Mikkel Drejer, Jimmy Kjellerup Dornhoff, Natasa Skrbic Mrkajic, Dan Nybro Lindqvist, Hans Christian Bruun Hansen and Lars Holm Rasmussen
Environmental Science: Processes & Impacts 24 (2) 277 (2022)
https://doi.org/10.1039/D1EM00364J

Presence of the carcinogen ptaquiloside in fern-based food products and traditional medicine: Four cases of human exposure

Lars Holm Rasmussen
Current Research in Food Science 4 557 (2021)
https://doi.org/10.1016/j.crfs.2021.08.004

A Novel Method for Determination of the Natural Toxin Ptaquiloside in Ground and Drinking Water

Natasa Skrbic, Ann-Katrin Pedersen, Sarah C. B. Christensen, Hans Christian Bruun Hansen and Lars Holm Rasmussen
Water 12 (10) 2852 (2020)
https://doi.org/10.3390/w12102852

Ptaquiloside from bracken (Pteridium spp.) promotes oral carcinogenesis initiated by HPV16 in transgenic mice

Rui M. Gil da Costa, Tiago Neto, Diogo Estêvão, et al.
Food & Function (2020)
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The role of bracken fern illudanes in bracken fern-induced toxicities

P.J. O’Connor, M.E. Alonso-Amelot, S.A. Roberts and A.C. Povey
Mutation Research/Reviews in Mutation Research 782 108276 (2019)
https://doi.org/10.1016/j.mrrev.2019.05.001

Fate of ptaquiloside—A bracken fern toxin—In cattle

Paulo César dos Reis Aranha, Lars Holm Rasmussen, Godelind Alma Wolf-Jäckel, et al.
PLOS ONE 14 (6) e0218628 (2019)
https://doi.org/10.1371/journal.pone.0218628

Screening for Ptaquiloside in Ferns: Using Herbarium Specimens for Qualitative Mapping Purposes

Lars Holm Rasmussen and Henrik AErenlund Pedersen
Phytochemical Analysis 28 (6) 575 (2017)
https://doi.org/10.1002/pca.2707

Dissipation of pterosin B in acid soils – Tracking the fate of the bracken fern carcinogen ptaquiloside

Eirini Skourti-Stathaki, Frederik Clauson-Kaas, Kristian Koefoed Brandt, Lars Holm Rasmussen and Hans Christian Bruun Hansen
Chemosphere 165 453 (2016)
https://doi.org/10.1016/j.chemosphere.2016.09.050

Ptaquiloside, the Major Carcinogen of Bracken Fern, in the Pooled Raw Milk of Healthy Sheep and Goats: An Underestimated, Global Concern of Food Safety

Antonella Virgilio, Annamaria Sinisi, Valeria Russo, Salvatore Gerardo, Adriano Santoro, Aldo Galeone, Orazio Taglialatela-Scafati and Franco Roperto
Journal of Agricultural and Food Chemistry 63 (19) 4886 (2015)
https://doi.org/10.1021/acs.jafc.5b01937

Ptaquiloside-induced cytotoxicity in Crandall feline kidney and HGC-27 cells

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Oncology Letters 8 (4) 1839 (2014)
https://doi.org/10.3892/ol.2014.2378

The naturally occurring carcinogen ptaquiloside is present in groundwater below bracken vegetation

Frederik Clauson-Kaas, Pia H. Jensen, Ole S. Jacobsen, René K. Juhler and Hans Christian B. Hansen
Environmental Toxicology and Chemistry 33 (5) 1030 (2014)
https://doi.org/10.1002/etc.2533

Determination of ptaquiloside and pterosin B derived from bracken (Pteridium aquilinum) in cattle plasma, urine and milk

Paulo César Reis Aranha, Hans Christian Bruun Hansen, Lars Holm Rasmussen, Bjarne W. Strobel and Christian Friis
Journal of Chromatography B 951-952 44 (2014)
https://doi.org/10.1016/j.jchromb.2014.01.022

Quantification of Ptaquiloside and Pterosin B in Soil and Groundwater Using Liquid Chromatography−Tandem Mass Spectrometry (LC−MS/MS)

Pia H. Jensen, Ole S. Jacobsen, Hans Christian B. Hansen and René K. Juhler
Journal of Agricultural and Food Chemistry 56 (21) 9848 (2008)
https://doi.org/10.1021/jf801986u

Ptaquiloside, the major toxin of bracken, and related terpene glycosides: chemistry, biology and ecology

Kiyoyuki Yamada, Makoto Ojika and Hideo Kigoshi
Natural Product Reports 24 (4) 798 (2007)
https://doi.org/10.1039/b614160a

Opinion of the Scientific Panel on contaminants in the food chain [CONTAM] related to cyanogenic compounds as undesirable substances in animal feed

EFSA Journal 5 (2) 434 (2007)
https://doi.org/10.2903/j.efsa.2007.434

Ptaquiloside Z, a new toxic unstable sesquiterpene glucoside from the neotropical bracken fern pteridium aquilinum var. caudatum

Uvidelio Francisco Castillo, Makoto Ojika, Miguel Alonso-Amelot and Youji Sakagami
Bioorganic & Medicinal Chemistry 6 (11) 2229 (1998)
https://doi.org/10.1016/S0968-0896(98)00168-0

Bracken ptaquiloside in milk

Miguel E. Alonso-Amelot, Uvidelio Castillo, Barry L. Smith and Denis R. Lauren
Nature 382 (6592) 587 (1996)
https://doi.org/10.1038/382587a0

Comparative dynamics of ptaquiloside and pterosin B in the two varieties (caudatum and arachnoideum) of neotropical Bracken Fern (Pteridium aquilinum L. Kuhn)

Miguel E. Alonso-Amelot, Serbia Rodulfo-Baechler and Ramón Jaimes-Espinoza
Biochemical Systematics and Ecology 23 (7-8) 709 (1995)
https://doi.org/10.1016/0305-1978(95)00071-2